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Virology

Head of Institute:
Prof. Dr. med. Klaus Überla
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PD. Dr. Niels Schaft PhD

phone:
+49 9131 85-31127
fax:
+49 9131 85-32931


institution:
position:
RNA-group; Research Group Leader
 

The main focus of my research in the RNA-group is the transfer of tumor-specific receptors into T cells by RNA-transfection. Tumor-specific full-length T-cell receptors (TCRs) as well as chimeric antigen receptors (CARs) are introduced into T cells by this technology. This enables these cells to lyse tumor cells. Currently we are working on: 1) the clinical application of CAR-T cells against solid tumors, mainly melanoma, 2) the optimization of CAR-T cells specific for several cancer antigens, and 3) TCR-transfer to alpha/beta and gamma/delta T cells to treat viral infections and cancer.

Publications:
http://www.ncbi.nlm.nih.gov/pubmed/?term=Schaft+N

 
address:
Hartmannstraße 14
91052 Erlangen
building:
Kussmaul research campus


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