Publikationsliste des Virologischen Instituts
Die Publikationsliste der letzten 5 Jahre wurde mit dem automatischen System zur Erhebung und Evaluation von Leistungsdaten für die universitäre Forschung EVALuna Biblio erstellt.
2024
- (2024) STAT6-induced production of mucus and resistin-like molecules in lung Club cells does not protect against helminth or influenza A virus infection. Eur J Immunol. 2024;54(1):
- (2024) B-cell and antibody responses to SARS-CoV-2: infection, vaccination, and hybrid immunity. Cell Mol Immunol. 2024;21(2): 144-158
- (2024) Validation of a Parvovirus B19 NAT Assay for Screening of Umbilical Cord Blood for Allogenic Hematopoietic Stem Cell Donation. Transfus Med Hemother. 2024;51(1): 48-51
- (2024) Tixagevimab/cilgavimab for the prevention of COVID-19 in vaccine-refractory patients with autoimmune diseases: a prospective cohort study. Rheumatology (Oxford). 2024;63(5): 1377-1383
- (2024) Clinical and immunological benefits of full primary COVID-19 vaccination in individuals with SARS-CoV-2 breakthrough infections: A prospective cohort study in non-hospitalized adults. J Clin Virol. 2024;170():
- (2024) Validation of nuclear receptor RORγ isoform 1 as a novel host-directed antiviral target based on the modulation of cholesterol levels. Antiviral Res. 2024;221():
2023
- (2023) Light-Driven Catalyst-Free Access to Phthalazines: Entry to Antiviral Model Drugs by Merging Domino Reactions European J Org Chem. 2023;26(5):
- (2023) Cervical intraepithelial neoplasia grade 3: development during pregnancy and postpartum. Arch Gynecol Obstet. 2023;307(5): 1567-1572
- (2023) Cellular and humoral immune responses to SARS-CoV-2 vaccination in patients after CD19.CAR T-cell therapy. Blood Adv. 2023;7(10): 2066-2069
- (2023) HIV-1 neutralizing antibodies provide sterilizing immunity by blocking infection of the first cells. Cell Rep Med. 2023;4(10):
- (2023) Identification of CD4+T Cells targeting DM-sensitive Antigens in mismatched HLA-DP Alleles as Mediators for selective Graftversus-Leukemia Effect Oncology Research and Treatment. 2023;46 Suppl 5(): 196-196
- (2023) Human MCTS1-dependent translation of JAK2 is essential for IFN-γ immunity to mycobacteria. Cell. 2023;186(23): 5114-5134.e27
- (2023) Modulation of immune responses to liposomal vaccines by intrastructural help. Eur J Pharm Biopharm. 2023;192(): 112-125
- (2023) Antigen-dependent modulation of immune responses to antigen-Fc fusion proteins by Fc-effector functions. Front Immunol. 2023;14():
- (2023) ORF3c is expressed in SARS-CoV-2-infected cells and inhibits innate sensing by targeting MAVS. EMBO Rep. 2023;24(12):
- (2023) Transcriptional Targeting of Dendritic Cells Using an Optimized Human Fascin1 Gene Promoter. Int J Mol Sci. 2023;24(23):
- (2023) Population-based study of the durability of humoral immunity after SARS-CoV-2 infection. Front Immunol. 2023;14():
- (2023) Functional effects of altered immune phenotype in patients cured from DLBCL Oncology Research and Treatment. 2023;46 Suppl 5(): 273-273
- (2023) SARS-CoV-2 variants with NSP12 P323L/G671S mutations display enhanced virus replication in ferret upper airways and higher transmissibility. Cell Rep. 2023;42(9):
- (2023) Precise excision of HTLV-1 provirus with a designer-recombinase. Mol Ther. 2023;31(7): 2266-2285
- (2023) An antiviral targeting strategy based on the inducible interference with cytomegalovirus nuclear egress complex. Antiviral Res. 2023;212():
- (2023) Patient-reported reactogenicity and safety of COVID-19 vaccinations vs. comparator vaccinations: a comparative observational cohort study. BMC Med. 2023;21(1):
- (2023) Lipid Accumulation in Host Cells Promotes SARS-CoV-2 Replication. Viruses. 2023;15(4):
- (2023) Milk Transmission of Mammalian Retroviruses. Microorganisms. 2023;11(7):
- (2023) Analysis of SARS-CoV-2 Spike Protein Variants with Recombinant Reporter Viruses Created from a Bacmid System. Int J Mol Sci. 2023;24(9):
- (2023) Comparison of a Genotype 1 and a Genotype 2 Macaque Foamy Virus env Gene Indicates Distinct Infectivity and Cell-Cell Fusion but Similar Tropism and Restriction of Cell Entry by Interferon-Induced Transmembrane Proteins. Viruses. 2023;15(2):
- (2023) A frequent SNP in TRIM5α strongly enhances the innate immune response against LINE-1 elements. Front Immunol. 2023;14():
- (2023) Cytomegalovirus cyclin-dependent kinase ortholog vCDK/pUL97 undergoes regulatory interaction with human cyclin H and CDK7 to codetermine viral replication efficiency. Virus Res. 2023;335():
- (2023) Reactogenicity and safety of COVID-19 primary immunisation and booster vaccination regimens: a comparative observational cohort study. BMC Med. 2023;21(1):
- (2023) Definition of a New HLA B*52-Restricted Rev CTL Epitope Targeted by an HIV-1-Infected Controller. Viruses. 2023;15(2):
- (2023) Ex Vivo Blockade of the PD-1 Pathway Improves Recall IFNγ Responses of HIV-Infected Persons on Antiretroviral Therapy. Vaccines (Basel). 2023;11(2):
- (2023) A Genetically Encoded Dark-to-Bright Biosensor for Visualisation of Granzyme-Mediated Cytotoxicity. Int J Mol Sci. 2023;24(17):
- (2023) HIV-1-specific T-cells in an HIV-1-infected but HIV-1 antibody negative patient on long-term antiretroviral therapy. HIV Med. 2023;24 Suppl 1(): 65-66
- (2023) Propagation of SARS-CoV-2 in a Closed Cell Culture Device: Potential GMP Compatible Production Platform for Live-Attenuated Vaccine Candidates under BSL-3 Conditions? Viruses. 2023;15(2):
- (2023) Critical illness and early mortality of brain cancer patients due to reactivation of human cytomegalovirus (HCMV) during radiotherapy of the brain - updated results of the prospective GLIO-CMV01 trial Strahlenther Onkol. 2023;199 Suppl 1(): S33-S34
- (2023) Colposcopic Accuracy in the Detection of cervical Intraepithelial Neoplasia Geburtsh Frauenheilk. 2023;83(6): 755-757
- (2023) SARS-CoV-2 Spike Protein Is Capable of Inducing Cell-Cell Fusions Independent from Its Receptor ACE2 and This Activity Can Be Impaired by Furin Inhibitors or a Subset of Monoclonal Antibodies. Viruses. 2023;15(7):
- (2023) Autofluorescent Artemisinin-Benzimidazole Hybrids via Organo-Click Reaction: Study of Antiviral Properties and Mode of Action in Living Cells. Chemistry. 2023;29(48):
- (2023) Effect of mucosal adjuvant IL-1β on heterotypic immunity in a pig influenza model. Front Immunol. 2023;14():
- (2023) Class switch toward noninflammatory, spike-specific IgG4 antibodies after repeated SARS-CoV-2 mRNA vaccination. Sci Immunol. 2023;8(79):
- (2023) Assessment of Covalently Binding Warhead Compounds in the Validation of the Cytomegalovirus Nuclear Egress Complex as an Antiviral Target. Cells. 2023;12(8):
- (2023) Murine cytomegalovirus reactivation concomitant with acute graft-versus-host disease is controlled by antibodies. JCI Insight. 2023;8(5):
- (2023) Cytology and HPV Co-Testing for Detection of Vaginal Intraepithelial Neoplasia: A Retrospective Study. Cancers (Basel). 2023;15(18):
- (2023) Alcohol-sourced acetate impairs T cell function by promoting cortactin acetylation. iScience. 2023;26(7):
- (2023) XCR1 expression distinguishes human conventional dendritic cell type 1 with full effector functions from their immediate precursors. Proc Natl Acad Sci U S A. 2023;120(33):
- (2023) Spike and nsp6 are key determinants of SARS-CoV-2 Omicron BA.1 attenuation. Nature. 2023;615(7950): 143-150
- (2023) Fatal Puumala Hantavirus Infection in a Patient with Common Variable Immunodeficiency (CVID). Microorganisms. 2023;11(2):
- (2023) Detection of pre-existing neutralizing antibodies against Ad26 in HIV-1-infected individuals not responding to the Ad26.COV2.S vaccine. Infection. 2023;51(6): 1657-1667
- (2023) In mouse kidney endogenous transmembrane serine protease 2 (TMPRSS2) contributes to proteolytic processing and activation of the epithelial sodium channel (ENaC) Physiology (Bethesda). 2023;38 Suppl 1():
- (2023) A second update on mapping the human genetic architecture of COVID-19. Nature. 2023;621(7977): E7-E26
- (2023) The Interactive Complex between Cytomegalovirus Kinase vCDK/pUL97 and Host Factors CDK7-Cyclin H Determines Individual Patterns of Transcription in Infected Cells. Int J Mol Sci. 2023;24(24):
- (2023) Kaposi's sarcoma-associated herpesvirus glycoprotein K8.1 is critical for infection in a cell-specific manner and functions at the attachment step on keratinocytes. J Virol. 2023;97(10):
- (2023) Re-Analysis of the Widely Used Recombinant Murine Cytomegalovirus MCMV-m157luc Derived from the Bacmid pSM3fr Confirms Its Hybrid Nature. Int J Mol Sci. 2023;24(18):
- (2023) Results of Tick-Borne Encephalitis Virus (TBEV) Diagnostics in an Endemic Area in Southern Germany, 2007 to 2022. Viruses. 2023;15(12):
- (2023) Role of spike in the pathogenic and antigenic behavior of SARS-CoV-2 BA.1 Omicron. bioRxiv. 2023;():
- (2023) Deficiency for SAMHD1 activates MDA5 in a cGAS/STING-dependent manner. J Exp Med. 2023;220(1):
- (2023) Management of Cervical Intraepithelial Neoplasia in Pregnant Women. Anticancer Res. 2023;43(7): 3153-3158
- (2023) Combined Treatment with Host-Directed and Anticytomegaloviral Kinase Inhibitors: Mechanisms, Synergisms and Drug Resistance Barriers. Pharmaceutics. 2023;15(12):
- (2023) Antibodies Against Glutamic Acid Decarboxylase 65 Are Locally Produced in the CSF and Arise During Affinity Maturation. Neurol Neuroimmunol Neuroinflamm. 2023;10(3):
- (2023) DNA extraction from clotted blood in genotyping quality. Biotechniques. 2023;74(1): 23-29
- (2023) Bind&Bite: covalently stabilized heterodimeric coiled-coil peptides for the site-selective, cysteine-free chemical modification of proteins. RSC Chem Biol. 2023;4(10): 794-803
2022
- (2022) Anti-SARS-CoV-2 Inhibitory Profile of New Quinoline Compounds in Cell Culture-Based Infection Models. Chemistry. 2022;28(4):
- (2022) A pair of noncompeting neutralizing human monoclonal antibodies protecting from disease in a SARS-CoV-2 infection model. Eur J Immunol. 2022;52(5): 770-783
- (2022) Importance of human papillomavirus vaccines in the prevention of cancer Onkologie (Heidelberg, Germany). 2022;28(1): 5-14
- (2022) Covalent coupling of HIV-1 glycoprotein trimers to biodegradable calcium phosphate nanoparticles via genetically encoded aldehyde-tags. Acta Biomater. 2022;140(): 586-600
- (2022) Rubella vaccine-induced granulomas are a novel phenotype with incomplete penetrance of genetic defects in cytotoxicity. J Allergy Clin Immunol. 2022;149(1): 388-399.e4
- (2022) Concordance Rate of Colposcopy in Detecting Cervical Intraepithelial Lesions. Diagnostics (Basel). 2022;12(10):
- (2022) 'Shared-Hook' and 'Changed-Hook' Binding Activities of Herpesviral Core Nuclear Egress Complexes Identified by Random Mutagenesis. Cells. 2022;11(24):
- (2022) Recombinant Human Cytomegalovirus Expressing an Analog-Sensitive Kinase pUL97 as Novel Tool for Functional Analyses. Viruses. 2022;14(10):
- (2022) Higher Infection Risk among Health Care Workers and Lower Risk among Smokers Persistent across SARS-CoV-2 Waves-Longitudinal Results from the Population-Based TiKoCo Seroprevalence Study. Int J Environ Res Public Health. 2022;19(24):
- (2022) Nsp16 shields SARS-CoV-2 from efficient MDA5 sensing and IFIT1-mediated restriction. EMBO Rep. 2022;23(12):
- (2022) Immune suppression of vaccine-induced CD8+ T-cell responses by gamma retrovirus envelope is mediated by interleukin-10-producing CD4+ T cells. Front Immunol. 2022;13():
- (2022) Mucosal vaccination with a viral vector vaccine induces robust lung-resident T cell responses and protects against 4T1 metastasis Eur J Immunol. 2022;52 Suppl 1(): 72-72
- (2022) Dynamics of humoral and cellular immune responses after homologous and heterologous SARS-CoV-2 vaccination with ChAdOx1 nCoV-19 and BNT162b2. EBioMedicine. 2022;85():
- (2022) A Peptide Inhibitor of the Human Cytomegalovirus Core Nuclear Egress Complex. Pharmaceuticals (Basel). 2022;15(9):
- (2022) Functionality of antigen-specific T cell receptor repertoires after SARS-CoV-2 vaccination Eur J Immunol. 2022;52 Suppl 1(): 13-13
- (2022) In-depth analysis of T cell immunity and antibody responses in heterologous prime-boost-boost vaccine regimens against SARS-CoV-2 and Omicron variant. Front Immunol. 2022;13():
- (2022) Highly Conserved Interaction Profiles between Clinically Relevant Mutants of the Cytomegalovirus CDK-like Kinase pUL97 and Human Cyclins: Functional Significance of Cyclin H. Int J Mol Sci. 2022;23(19):
- (2022) Enhanced Spike-specific, but attenuated Nucleocapsid-specific T cell responses upon SARS-CoV-2 breakthrough versus non-breakthrough infections. Front Immunol. 2022;13():
- (2022) Protective mucosal immunity against SARS-CoV-2 after heterologous systemic RNA-mucosal adenoviral vector immunization Eur J Immunol. 2022;52 Suppl 1(): 56-57
- (2022) Cytology and hrHPV for cervical cancer screening assessment Geburtsh Frauenheilk. 2022;82(10): E171-E172
- (2022) Cervical intraepithelial neoplasia grade 2/3: development during pregnancy and postpartum Geburtsh Frauenheilk. 2022;82(10): E171-E171
- (2022) Milk Transmission of HTLV-1 and the Need for Innovative Prevention Strategies. Front Med (Lausanne). 2022;9():
- (2022) Viral Mimicry of Interleukin-17A by SARS-CoV-2 ORF8. MBio. 2022;13(2):
- (2022) SMYD2 Inhibition Downregulates TMPRSS2 and Decreases SARS-CoV-2 Infection in Human Intestinal and Airway Epithelial Cells. Cells. 2022;11(8):
- (2022) 'Come together'-The Regulatory Interaction of Herpesviral Nuclear Egress Proteins Comprises Both Essential and Accessory Functions. Cells. 2022;11(11):
- (2022) The Oligomeric Assemblies of Cytomegalovirus Core Nuclear Egress Proteins Are Associated with Host Kinases and Show Sensitivity to Antiviral Kinase Inhibitors. Viruses. 2022;14(5):
- (2022) Cyclin-Dependent Kinases (CDKs) and the Human Cytomegalovirus-Encoded CDK Ortholog pUL97 Represent Highly Attractive Targets for Synergistic Drug Combinations. Int J Mol Sci. 2022;23(5):
- (2022) Inhibitors of Deubiquitinating Enzymes Interfere with the SARS-CoV-2 Papain-like Protease and Block Virus Replication In Vitro. Viruses. 2022;14(7):
- (2022) Synergistic Antiviral Activity of Pamapimod and Pioglitazone against SARS-CoV-2 and Its Variants of Concern. Int J Mol Sci. 2022;23(12):
- (2022) The crystal structure of the varicella-zoster Orf24-Orf27 nuclear egress complex spotlights multiple determinants of herpesvirus subfamily specificity. J Biol Chem. 2022;298(3):
- (2022) Design and Functional Characterization of HIV-1 Envelope Protein-Coupled T Helper Liposomes. Pharmaceutics. 2022;14(7):
- (2022) Antibodies Targeting KSHV gH/gL Reveal Distinct Neutralization Mechanisms. Viruses. 2022;14(3):
- (2022) Synthesis, molecular features and biological activities of modified plant polysaccharides. Carbohydr Polym. 2022;289():
- (2022) Attenuation of SARS-CoV-2 replication and associated inflammation by concomitant targeting of viral and host cap 2'-O-ribose methyltransferases. EMBO J. 2022;41(17):
- (2022) Differential induction of lung-resident memory T cells through infection or viral vector immunization Eur J Immunol. 2022;52 Suppl 1(): 150-151
- (2022) Reactogenicity after heterologous and homologous COVID-19 prime-boost vaccination regimens: descriptive interim results of a comparative observational cohort study. BMC Infect Dis. 2022;22(1):
- (2022) Ubiquitous Micro-Modular Homologies among Genomes from Viruses to Bacteria to Human Mitochondrial DNA: Platforms for Recombination during Evolution? Viruses. 2022;14(5):
- (2022) Smaller, Stronger, More Stable: Peptide Variants of a SARS-CoV-2 Neutralizing Miniprotein. Int J Mol Sci. 2022;23(11):
- (2022) Transmembrane serine protease 2 (TMPRSS2) proteolytically activates the epithelial sodium channel (ENaC) by cleaving the channel's γ-subunit. J Biol Chem. 2022;298(6):
- (2022) HDAC inhibitors Panobinostat and Romidepsin enhance tax transcription in HTLV-1-infected cell lines and freshly isolated patients' T-cells. Front Immunol. 2022;13():
- (2022) [Erratum to: Bornavirus encephalitis as a differential diagnosis to seronegative autoimmune encephalitis]. Nervenarzt. 2022;93(8): 838-839
- (2022) Continuous monitoring of SARS-CoV-2 seroprevalence in children using residual blood samples from routine clinical chemistry. Clin Chem Lab Med. 2022;60(6): 941-951
- (2022) Homologous COVID-19 BNT162b2 mRNA Vaccination at a German Tertiary Care University Hospital: A Survey-Based Analysis of Reactogenicity, Safety, and Inability to Work among Healthcare Workers. Vaccines (Basel). 2022;10(5):
- (2022) Novel, orally available immune modulator MP1032 with pan-variant anti-SARS-CoV-2 and anti-inflammatory activity Eur J Immunol. 2022;52 Suppl 1(): 176-177
- (2022) Cytology and High-Risk Human Papillomavirus Test for Cervical Cancer Screening Assessment. Diagnostics (Basel). 2022;12(7):
- (2022) Mucosal immunization with an adenoviral vector vaccine confers superior protection against RSV compared to natural immunity. Front Immunol. 2022;13():
- (2022) Time Trend in SARS-CoV-2 Seropositivity, Surveillance Detection- and Infection Fatality Ratio until Spring 2021 in the Tirschenreuth County-Results from a Population-Based Longitudinal Study in Germany. Viruses. 2022;14(6):
- (2022) Impaired IL-23-dependent induction of IFN-γ underlies mycobacterial disease in patients with inherited TYK2 deficiency. J Exp Med. 2022;219(10):
- (2022) Characterization of SARS-CoV-2 Escape Mutants to a Pair of Neutralizing Antibodies Targeting the RBD and the NTD. Int J Mol Sci. 2022;23(15):
- (2022) Characterization of Serum and Mucosal SARS-CoV-2-Antibodies in HIV-1-Infected Subjects after BNT162b2 mRNA Vaccination or SARS-CoV-2 Infection. Viruses. 2022;14(3):
- (2022) Transmembrane serine protease 2 (TMPRSS2) is involved in proteolytic activation of the epithelial sodium channel (ENaC) in mouse cortical collecting duct (mCCDcl1) cells Acta Physiol (Oxf). 2022;236 Suppl 725(): 149-151
- (2022) Transmembrane serine protease 2 (TMPRSS2) proteolytically activates the epithelial sodium channel (ENaC) by cleaving the channel's gamma-subunit Acta Physiol (Oxf). 2022;236 Suppl 725(): 294-295
- (2022) Alternative NF-κB Signaling Discriminates Induction of the Tumor Marker Fascin by the Viral Oncoproteins Tax-1 and Tax-2 of Human T-Cell Leukemia Viruses. Cancers (Basel). 2022;14(3):
- (2022) Correction for Elsayed et al., "Intrastructural Help: Harnessing T Helper Cells Induced by Licensed Vaccines for Improvement of HIV Env Antibody Responses to Virus-Like Particle Vaccines". J Virol. 2022;96(3):
- (2022) Neutralizing Antibodies Limit Cell-Associated Spread of Human Cytomegalovirus in Epithelial Cells and Fibroblasts. Viruses. 2022;14(2):
- (2022) Three exposures to the spike protein of SARS-CoV-2 by either infection or vaccination elicit superior neutralizing immunity to all variants of concern. Nat Med. 2022;28(3): 496-503
- (2022) Comparative Immunogenicity of COVID-19 Vaccines in a Population-Based Cohort Study with SARS-CoV-2-Infected and Uninfected Participants. Vaccines (Basel). 2022;10(2):
- (2022) Prevalence and patterns of HIV drug resistance in patients with suspected virological failure in North-Western Tanzania. J Antimicrob Chemother. 2022;77(2): 483-491
- (2022) [Bornavirus encephalitis as a differential diagnosis to seronegative autoimmune encephalitis]. Nervenarzt. 2022;93(8): 835-837
- (2022) SARS-CoV-2 variants show temperature-dependent enhanced polymerase activity in the upper respiratory tract and high transmissibility. bioRxiv. 2022;():
- (2022) Detection of asymptomatic SARS-CoV-2 infections in daycare centers, schools, and companies for regional pandemic containment by a PCR testing laboratory cooperative between July 2021 and June 2022. GMS Hyg Infect Control. 2022;17():
- (2022) The Trimeric Artesunate Analog TF27, a Broadly Acting Anti-Infective Model Drug, Exerts Pronounced Anti-SARS-CoV-2 Activity Spanning Variants and Host Cell Types. Pharmaceutics. 2022;15(1):
- (2022) Active monitoring of adverse reactions following COVID-19 and other vaccinations: a feasibility study as part of the CoVaKo project. Pilot Feasibility Stud. 2022;8(1):
2021
- (2021) Validation of a SARS-CoV-2 RNA RT-PCR assay for high-throughput testing in blood of COVID-19 convalescent plasma donors and patients. Transfusion. 2021;61(2): 368-374
- (2021) Rapid response flow cytometric assay for the detection of antibody responses to SARS-CoV-2. Eur J Clin Microbiol Infect Dis. 2021;40(4): 751-759
- (2021) Exploiting the Amazing Diversity of Natural Source-Derived Polysaccharides: Modern Procedures of Isolation, Engineering, and Optimization of Antiviral Activities. Polymers (Basel). 2021;13(1):
- (2021) Investigational Antiviral Therapy Models for the Prevention and Treatment of Congenital Cytomegalovirus Infection during Pregnancy. Antimicrob Agents Chemother. 2021;65(1):
- (2021) Molecular diagnosis of polymicrobial brain abscesses with 16S-rDNA-based next-generation sequencing. Clin Microbiol Infect. 2021;27(1): 76-82
- (2021) Pearls & Oy-sters: SARS-CoV-2 Infection of the CNS in a Patient With Meningeosis Carcinomatosa. Neurology. 2021;96(10): 496-499
- (2021) Human herpesvirus 8 molecular mimicry of ephrin ligands facilitates cell entry and triggers EphA2 signaling. PLoS Biol. 2021;19(9):
- (2021) The HIV 5' Gag Region Displays a Specific Nucleotide Bias Regulating Viral Splicing and Infectivity. Viruses. 2021;13(6):
- (2021) Complement Activation in Kidneys of Patients With COVID-19. Front Immunol. 2021;11():
- (2021) Characterizing the Interaction between the HTLV-1 Transactivator Tax-1 with Transcription Elongation Factor ELL2 and Its Impact on Viral Transactivation. Int J Mol Sci. 2021;22(24):
- (2021) Latency Reversing Agents: Kick and Kill of HTLV-1? Int J Mol Sci. 2021;22(11):
- (2021) Translocated microbiome composition determines immunological outcome in treated HIV infection. Cell. 2021;184(15): 3899-3914.e16
- (2021) SARS-CoV-2 worldwide replication drives rapid rise and selection of mutations across the viral genome: a time-course study - potential challenge for vaccines and therapies. EMBO Mol Med. 2021;13(6):
- (2021) Cloning of a Passage-Free SARS-CoV-2 Genome and Mutagenesis Using Red Recombination. Int J Mol Sci. 2021;22(19):
- (2021) The Complex Regulatory Role of Cytomegalovirus Nuclear Egress Protein pUL50 in the Production of Infectious Virus. Cells. 2021;10(11):
- (2021) Methodological Development of a Multi-Readout Assay for the Assessment of Antiviral Drugs against SARS-CoV-2. Pathogens. 2021;10(9):
- (2021) Properties of Oligomeric Interaction of the Cytomegalovirus Core Nuclear Egress Complex (NEC) and Its Sensitivity to an NEC Inhibitory Small Molecule. Viruses. 2021;13(3):
- (2021) Phenotypical Characterization of the Nuclear Egress of Recombinant Cytomegaloviruses Reveals Defective Replication upon ORF-UL50 Deletion but Not pUL50 Phosphosite Mutation. Viruses. 2021;13(2):
- (2021) A placental specific miRNA miR-517a-3p exerts anti-human cytomegalovirus activity. Placenta. 2021;112(): 62-65
- (2021) Combinatorial Drug Treatments Reveal Promising Anticytomegaloviral Profiles for Clinically Relevant Pharmaceutical Kinase Inhibitors (PKIs). Int J Mol Sci. 2021;22(2):
- (2021) High Th2 cytokine levels and upper airway inflammation in human inherited T-bet deficiency. J Exp Med. 2021;218(8):
- (2021) Exploring the Human Cytomegalovirus Core Nuclear Egress Complex as a Novel Antiviral Target: A New Type of Small Molecule Inhibitors. Viruses. 2021;13(3):
- (2021) Gut as viral reservoir: lessons from gut viromes, HIV and COVID-19. Gut. 2021;70(9): 1605-1608
- (2021) Symptoms, SARS-CoV-2 Antibodies, and Neutralization Capacity in a Cross Sectional-Population of German Children. Front Pediatr. 2021;9():
- (2021) Interleukin-3 is a predictive marker for severity and outcome during SARS-CoV-2 infections. Nat Commun. 2021;12(1):
- (2021) SAMHD1 … and Viral Ways around It. Viruses. 2021;13(3):
- (2021) Recognize Yourself-Innate Sensing of Non-LTR Retrotransposons. Viruses. 2021;13(1):
- (2021) Functional Relevance of the Interaction between Human Cyclins and the Cytomegalovirus-Encoded CDK-Like Protein Kinase pUL97. Viruses. 2021;13(7):
- (2021) Biographical Feature: Bernhard Fleckenstein. J Virol. 2021;95(17):
- (2021) Human papilloma virus genotype distribution in women with premalignant or malignant lesions of the uterine cervix. Arch Gynecol Obstet. 2021;304(3): 751-758
- (2021) A Barcoded Flow Cytometric Assay to Explore the Antibody Responses Against SARS-CoV-2 Spike and Its Variants. Front Immunol. 2021;12():
- (2021) Replication of Influenza A Virus in Secondary Lymphatic Tissue Contributes to Innate Immune Activation. Pathogens. 2021;10(5):
- (2021) T Cell Immunity against Influenza: The Long Way from Animal Models Towards a Real-Life Universal Flu Vaccine. Viruses. 2021;13(2):
- (2021) Protective mucosal immunity against SARS-CoV-2 after heterologous systemic prime-mucosal boost immunization. Nat Commun. 2021;12(1):
- (2021) CARs-A New Perspective to HCMV Treatment. Viruses. 2021;13(8):
- (2021) Spike residue 403 affects binding of coronavirus spikes to human ACE2. Nat Commun. 2021;12(1):
- (2021) CRNKL1 Is a Highly Selective Regulator of Intron-Retaining HIV-1 and Cellular mRNAs. MBio. 2021;12(1):
- (2021) Spectrum Bias and Individual Strengths of SARS-CoV-2 Serological Tests-A Population-Based Evaluation. Diagnostics (Basel). 2021;11(10):
- (2021) Estimates and Determinants of SARS-Cov-2 Seroprevalence and Infection Fatality Ratio Using Latent Class Analysis: The Population-Based Tirschenreuth Study in the Hardest-Hit German County in Spring 2020. Viruses. 2021;13(6):
- (2021) Decorated and Encapsulated: Virus-Like Particles Against Viral Infections. Vaccines (Basel). 2021;9(3):
- (2021) Heterologous prime-boost vaccination with ChAdOx1 nCoV-19 and BNT162b2. Lancet Infect Dis. 2021;21(9): 1212-1213
- (2021) SARS-CoV-2 N gene dropout and N gene Ct value shift as indicator for the presence of B.1.1.7 lineage in a commercial multiplex PCR assay. Clin Microbiol Infect. 2021;27(9): 1353.e1-1353.e5
- (2021) SARS-CoV-2-Seronegative Subjects Target CTL Epitopes in the SARS-CoV-2 Nucleoprotein Cross-Reactive to Common Cold Coronaviruses. Front Immunol. 2021;12():
- (2021) Adenoviral Vector DNA- and SARS-CoV-2 mRNA-Based Covid-19 Vaccines: Possible Integration into the Human Genome - Are Adenoviral Genes Expressed in Vector-based Vaccines? Virus Res. 2021;302():
- (2021) Iota-Carrageenan Inhibits Replication of SARS-CoV-2 and the Respective Variants of Concern Alpha, Beta, Gamma and Delta. Int J Mol Sci. 2021;22(24):
- (2021) Lectin from Triticum vulgaris (WGA) Inhibits Infection with SARS-CoV-2 and Its Variants of Concern Alpha and Beta. Int J Mol Sci. 2021;22(19):
- (2021) Quinine Inhibits Infection of Human Cell Lines with SARS-CoV-2. Viruses. 2021;13(4):
- (2021) Iota-carrageenan neutralizes SARS-CoV-2 and inhibits viral replication in vitro. PLoS ONE. 2021;16(2):
- (2021) The Saliva of Probands Sucking an Iota-Carrageenan Containing Lozenge Inhibits Viral Binding and Replication of the Most Predominant Common Cold Viruses and SARS-CoV-2. Int J Gen Med. 2021;14(): 5241-5249
- (2021) Successful treatment of COVID-19 infection with convalescent plasma in B-cell-depleted patients may promote cellular immunity. Eur J Immunol. 2021;51(10): 2478-2484
- (2021) Upregulation of CCR4 in activated CD8+ T cells indicates enhanced lung homing in patients with severe acute SARS-CoV-2 infection. Eur J Immunol. 2021;51(6): 1436-1448
- (2021) Diagnostic performance of four SARS-CoV-2 antibody assays in patients with COVID-19 or with bacterial and non-SARS-CoV-2 viral respiratory infections. Eur J Clin Microbiol Infect Dis. 2021;40(9): 1983-1997
- (2021) Plxdc family members are novel receptors for the rhesus monkey rhadinovirus (RRV). PLoS Pathog. 2021;17(3):
- (2021) Diazadispiroalkane Derivatives Are New Viral Entry Inhibitors. Antimicrob Agents Chemother. 2021;65(4):
- (2021) [COVID-19 effects on the kidney]. Pathologe. 2021;42(2): 183-187
- (2021) A Novel Strain-Specific Neutralizing Epitope on Glycoprotein H of Human Cytomegalovirus. J Virol. 2021;95(18):
- (2021) Anticancer activities of parthenolide in primary effusion lymphoma preclinical models. Mol Carcinog. 2021;60(8): 567-581
- (2021) SARS-CoV-2 and SARS-CoV Spike-Mediated Cell-Cell Fusion Differ in Their Requirements for Receptor Expression and Proteolytic Activation. J Virol. 2021;95(9):
- (2021) Reactogenicity Correlates Only Weakly with Humoral Immunogenicity after COVID-19 Vaccination with BNT162b2 mRNA (Comirnaty®). Vaccines (Basel). 2021;9(10):
- (2021) Correction to: Diagnostic performance of four SARS-CoV-2 antibody assays in patients with COVID-19 or with bacterial and non-SARS-CoV-2 viral respiratory infections. Eur J Clin Microbiol Infect Dis. 2021;40(9): 1999-2004
- (2021) PATIENTS WITH IMMUNE MEDIATED INFLAMMATORY DISEASES ARE OVERREPRESENTED IN LOW-FREQUENCY VIRAL SYMPTOM CLUSTERS Ann Rheum Dis. 2021;80 Suppl 1(): 996-997
- (2021) SARS-CoV-2-seronegative subjects target CTL epitopes in the SARS-CoV-2 nucleoprotein cross-reactive to common cold coronaviruses J Int AIDS Soc. 2021;24 Suppl 4(): 1-2
- (2021) SARS-CoV-2-seronegative HIV-1-infected subjects target CTL epitopes in the SARS-CoV-2 nucleoprotein cross-reactive to common cold coronaviruses Infection. 2021;49 Suppl 1(SUPPL 1): S30-S30
- (2021) On the way of assessing autonomous role of p6 in HIV-1 spread Eur Biophys J. 2021;50 Suppl 1(SUPPL 1): 180-180
- (2021) HIV-1 Viral Protein R Couples Metabolic Inflexibility With White Adipose Tissue Thermogenesis. Diabetes. 2021;70(9): 2014-2025
- (2021) Correction: Repertoire characterization and validation of gB-specific human IgGs directly cloned from humanized mice vaccinated with dendritic cells and protected against HCMV. PLoS Pathog. 2021;17(3):
- (2021) Is the BNT162b2 COVID-19 vaccine effective in elderly populations? Results from population data from Bavaria, Germany. PLoS ONE. 2021;16(11):
- (2021) Development of a PROTAC-Based Targeting Strategy Provides a Mechanistically Unique Mode of Anti-Cytomegalovirus Activity. Int J Mol Sci. 2021;22(23):
- (2021) Monocyte-derived transcriptome signature indicates antibody-dependent cellular phagocytosis as a potential mechanism of vaccine-induced protection against HIV-1. Elife. 2021;10():
- (2021) Antiviral Strategies Using Natural Source-Derived Sulfated Polysaccharides in the Light of the COVID-19 Pandemic and Major Human Pathogenic Viruses. Viruses. 2021;14(1):
- (2021) Enhancer analysis of the Drosophila zinc finger transcription factor Earmuff by gene targeting. Hereditas. 2021;158(1):
2020
- (2020) A Recombinant Rhesus Monkey Rhadinovirus Deleted of Glycoprotein L Establishes Persistent Infection of Rhesus Macaques and Elicits Conventional T Cell Responses. J Virol. 2020;94(2):
- (2020) Wedelolactone inhibits human cytomegalovirus replication by targeting distinct steps of the viral replication cycle. Antiviral Res. 2020;174():
- (2020) Patients with immune-mediated inflammatory diseases receiving cytokine inhibitors have low prevalence of SARS-CoV-2 seroconversion. Nat Commun. 2020;11(1):
- (2020) SARS-CoV-2 samples may escape detection because of a single point mutation in the N gene. Euro Surveill. 2020;25(39): 5-8
- (2020) Herpes simplex virus encephalitis after temporal lobe resection: an infrequent but treatable complication of epilepsy surgery. Eur J Neurol. 2020;27(10): e60-e61
- (2020) Transfer of HTLV-1 p8 and Gag to target T-cells depends on VASP, a novel interaction partner of p8. PLoS Pathog. 2020;16(9):
- (2020) Mass Spectrometry-Based Characterization of the Virion Proteome, Phosphoproteome, and Associated Kinase Activity of Human Cytomegalovirus. Microorganisms. 2020;8(6):
- (2020) Target verification of artesunate-related antiviral drugs: Assessing the role of mitochondrial and regulatory proteins by click chemistry and fluorescence labeling. Antiviral Res. 2020;180():
- (2020) The peptidyl-prolyl cis/trans isomerase Pin1 interacts with three early regulatory proteins of human cytomegalovirus. Virus Res. 2020;285():
- (2020) A quantitative nuclear egress assay to investigate the nucleocytoplasmic capsid release of human cytomegalovirus. J Virol Methods. 2020;283():
- (2020) The Artemisinin-Derived Autofluorescent Compound BG95 Exerts Strong Anticytomegaloviral Activity Based on a Mitochondrial Targeting Mechanism. Int J Mol Sci. 2020;21(15):
- (2020) Human TRIM5α senses and restricts LINE-1 elements. Proc Natl Acad Sci U S A. 2020;117(30): 17965-17976
- (2020) Nuclear PYHIN proteins target the host transcription factor Sp1 thereby restricting HIV-1 in human macrophages and CD4+ T cells. PLoS Pathog. 2020;16(8):
- (2020) (Iso)Quinoline-Artemisinin Hybrids Prepared through Click Chemistry: Highly Potent Agents against Viruses. Chemistry. 2020;26(52): 12019-12026
- (2020) A novel positive feedback-loop between the HTLV-1 oncoprotein Tax and NF-κB activity in T-cells. Retrovirology. 2020;17(1):
- (2020) Cell Fusion Induced by a Fusion-Active Form of Human Cytomegalovirus Glycoprotein B (gB) Is Inhibited by Antibodies Directed at Antigenic Domain 5 in the Ectodomain of gB. J Virol. 2020;94(18):
- (2020) Nuclear Egress Complexes of HCMV and Other Herpesviruses: Solving the Puzzle of Sequence Coevolution, Conserved Structures and Subfamily-Spanning Binding Properties. Viruses. 2020;12(6):
- (2020) Human Cytomegalovirus Envelope Protein gpUL132 Regulates Infectious Virus Production through Formation of the Viral Assembly Compartment. MBio. 2020;11(5):
- (2020) Influence of Human Cytomegalovirus Glycoprotein O Polymorphism on the Inhibitory Effect of Soluble Forms of Trimer- and Pentamer-Specific Entry Receptors. J Virol. 2020;94(14):
- (2020) Naturally occurring variants in the transmembrane and cytoplasmic domains of the human Coxsackie- and adenovirus receptor have no impact on virus internalisation. Biochem Biophys Res Commun. 2020;527(2): 401-405
- (2020) Signal hotspot mutations in SARS-CoV-2 genomes evolve as the virus spreads and actively replicates in different parts of the world. Virus Res. 2020;289():
- (2020) Measuring the cellular memory B cell response after vaccination in patients after allogeneic stem cell transplantation. Ann Hematol. 2020;99(8): 1895-1906
- (2020) Conjugation of Native-Like HIV-1 Envelope Trimers onto Liposomes Using EDC/Sulfo-NHS Chemistry: Requirements and Limitations. Pharmaceutics. 2020;12(10):
- (2020) Early Mortality of Brain Cancer Patients and its Connection to Cytomegalovirus Reactivation During Radiochemotherapy. Clin Cancer Res. 2020;26(13): 3259-3270
- (2020) Repertoire characterization and validation of gB-specific human IgGs directly cloned from humanized mice vaccinated with dendritic cells and protected against HCMV. PLoS Pathog. 2020;16(7):
- (2020) Targeting zonulin and intestinal epithelial barrier function to prevent onset of arthritis. Nat Commun. 2020;11(1):
- (2020) Inherited human IFN-γ deficiency underlies mycobacterial disease. J Clin Invest. 2020;130(6): 3158-3171
- (2020) The Cytomegalovirus Protein Kinase pUL97:Host Interactions, Regulatory Mechanisms and Antiviral Drug Targeting. Microorganisms. 2020;8(4):
- (2020) Patterns of Autologous and Nonautologous Interactions Between Core Nuclear Egress Complex (NEC) Proteins of α-, β- and γ-Herpesviruses. Viruses. 2020;12(3):
- (2020) The trimeric artesunate derivative TF27 exerts strong anti-cytomegaloviral efficacy: Focus on prophylactic efficacy and oral treatment of immunocompetent mice. Antiviral Res. 2020;178():
- (2020) Phosphosite Analysis of the Cytomegaloviral mRNA Export Factor pUL69 Reveals Serines with Critical Importance for Recruitment of Cellular Proteins Pin1 and UAP56/URH49. J Virol. 2020;94(8):
- (2020) Differential upregulation of host cell protein kinases by the replication of α-, β- and γ-herpesviruses provides a signature of virus-specific signalling. J Gen Virol. 2020;101(3): 284-289
- (2020) High-resolution crystal structures of two prototypical β- and γ-herpesviral nuclear egress complexes unravel the determinants of subfamily specificity. J Biol Chem. 2020;295(10): 3189-3201
- (2020) Modulation of Vaccine-Induced HIV-1-Specific Immune Responses by Co-Electroporation of PD-L1 Encoding DNA. Vaccines (Basel). 2020;8(1):
- (2020) Adult and Cord Blood-Derived High-Affinity gB-CAR-T Cells Effectively React Against Human Cytomegalovirus Infections. Hum Gene Ther. 2020;31(7-8): 423-439
- (2020) A highly potent trimeric derivative of artesunate shows promising treatment profiles in experimental models for congenital HCMV infection in vitro and ex vivo. Antiviral Res. 2020;175():
- (2020) Essential concepts are missing: Foreign DNA in food invades the organisms' cells and can lead to stochastic epigenetic alterations with a wide range of possible pathogenetic consequences. Clin Epigenetics. 2020;12(1):
- (2020) Innate signalling molecules as genetic adjuvants do not alter the efficacy of a DNA-based influenza A vaccine. PLoS ONE. 2020;15(4):
- (2020) Characterization of a universal screening approach for congenital CMV infection based on a highly-sensitive, quantitative, multiplex real-time PCR assay. PLoS ONE. 2020;15(1):
- (2020) Ethanol consumption inhibits TFH cell responses and the development of autoimmune arthritis. Nat Commun. 2020;11(1):
- (2020) Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections results in improved virus control but lethal immunopathology. PLoS Pathog. 2020;16(3): e1008340
- (2020) Variant morphology and random chromosomal integration of BK polyomavirus in posttransplant urothelial carcinomas. Mod Pathol. 2020;33(7): 1433-1442
- (2020) Killer cell proteases can target viral immediate-early proteins to control human cytomegalovirus infection in a noncytotoxic manner. PLoS Pathog. 2020;16(4):
- (2020) SARS-CoV-2 Infection in Pregnancy - a Review of the Current Literature and Possible Impact on Maternal and Neonatal Outcome Geburtsh Frauenheilk. 2020;80(4): 380-390
- (2020) CD4+ T Cells Induced by Tuberculosis Subunit Vaccine H1 Can Improve the HIV-1 Env Humoral Response by Intrastructural Help. Vaccines (Basel). 2020;8(4):
- (2020) Genetic Co-Administration of Soluble PD-1 Ectodomains Modifies Immune Responses against Influenza A Virus Induced by DNA Vaccination. Vaccines (Basel). 2020;8(4):
- (2020) IMU-838, a Developmental DHODH Inhibitor in Phase II for Autoimmune Disease, Shows Anti-SARS-CoV-2 and Broad-Spectrum Antiviral Efficacy In Vitro. Viruses. 2020;12(12):
- (2020) Immune-Modulating Drug MP1032 with SARS-CoV-2 Antiviral Activity In Vitro: A potential Multi-Target Approach for Prevention and Early Intervention Treatment of COVID-19. Int J Mol Sci. 2020;21(22):
- (2020) Rhesus Monkey Rhadinovirus Isolated from Hemangioma Tissue. MICROBIOLOGY RESOURCE ANNOUNCEMENTS. 2020;9(12):