Selected References

Virology

Head of Institute:
Prof. Dr. med. Klaus Überla

Selected References

  • Alt, M., Falk, J., Eis-Hübinger, A.M., Kropff, B., Sinzger, C., Krawczyk, A. (2018). Detection of antibody-secreting cells specific for the cytomegalovirus and herpes simplex virus surface antigens. J Immunol Methods. 462: 13-22.
  • Baraniak, I., Kropff, B., Ambrose, L., McIntosh, M., McLean, G.R., Pichon, S., Atkinson, C., Milne, R.S.B., Mach, M., Griffiths, P.D., Reeves, M.B. (2018). Protection from cytomegalovirus viremia following glycoprotein B vaccination is not dependent on neutralizing antibodies. Proc Natl Acad Sci USA. 115: 6273–6278.
  • Reuter, N., Reichel, A., Stilp, A.-C., Scherer, M., Stamminger, T. (2018). SUMOylation of IE2p86 is required for efficient autorepression of the human cytomegalovirus major immediate-early promoter. J Gen Virol. February 08, doi: 10.1099/jgv.0.001021.
  • Bootz, A., Karbach, A., Spindler, J., Kropff, B., Reuter, N., Sticht, H., Winkler, T.H., Britt, W.J., Mach, M. (2017). Protective capacity of neutralizing and non-neutralizing antibodies against glycoprotein B of cytomegalovirus. PLoS Pathog. 13(8): e1006601.
  • Kalser, J., Adler, B., Mach, M., Kropff, B., Puchhammer-Stöckl, E., Görzer, I. (2017). Differences in Growth Properties among Two Human Cytomegalovirus Glycoprotein O Genotypes. Front Microbiol. 8: 1609.
  • Reuter, N., Schilling, E.-M., Scherer, M., Müller, R., Stamminger, T. (2017). The ND10 Component Promyelocytic Leukemia Protein Acts as an E3 Ligase for SUMOylation of the Major Immediate Early Protein IE1 of Human Cytomegalovirus. J Virol. 91(10).
  • Tittlbach, H., Schneider, A., Strobel, J., Zimmermann, R., Maas, S., Gebhardt, B., Rauser, G., Mach, M., Mackensen, A., Winkler, T.H., Winkler, J. (2017). GMP-production of purified human B lymphocytes for the adoptive transfer in patients after allogeneic hematopoietic stem cell transplantation. J Transl Med. 15: 228.
  • Wu, Y., Prager, A., Boos, S., Resch, M., Brizic, I., Mach, M., Wildner, S., Scrivano, L., Adler, B. (2017). Human cytomegalovirus glycoprotein complex gH/gL/gO uses PDGFR-α as a key for entry. PLoS Pathog. 13: e1006281.
  • Sell, S., Dietz, M., Schneider, A., Holtappels, R., Mach, M., Winkler, T.H. (2015). Control of murine cytomegalovirus infection by γδ T cells. PLoS Pathog. 11: e1004481.
  • Wiegers, A.K., Sticht, H., Winkler, T.H., Britt, W.J., Mach, M. (2014). Identification of a Neutralizing Epitope within Antigenic Domain 5 of Glycoprotein B of Human Cytomegalovirus. J Virol. 89: 361-372.
  • Spindler, N., Diestel, U., Stump, J.D., Wiegers, A.K., Winkler, T.H., Sticht, H., Mach, M., Muller, Y.A. (2014). Structural basis for the recognition of human cytomegalovirus glycoprotein B by a neutralizing human antibody. PLoS Pathog. 10: e1004377.
  • Spindler, N., Rücker, P., Pötzsch, S., Diestel, U., Sticht, H., Martin-Parras, L., Winkler, T.H., Mach, M. (2013). Characterization of a discontinuous neutralizing epitope on glycoprotein B of human cytomegalovirus. J Virol. 87: 8927-8939.
  • Kropff, B., Burkhardt, C., Schott, J., Nentwich, J., Fisch, T., Britt, W., Mach, M. (2012). Glycoprotein N of human cytomegalovirus protects the virus from neutralizing antibodies. PLoS Pathog. 8(10): e1002999.
  • Pötzsch, S., Spindler, N., Wiegers, A.K., Fisch, T., Rücker, P., Sticht, H., Grieb, N., Baroti, T., Weisel, F., Stamminger, T., Martin-Parras, L., Mach, M., Winkler, T.H. (2011). B cell repertoire analysis identifies new antigenic domains on glycoprotein B of human cytomegalovirus which are target of neutralizing antibodies. PLoS Pathog. 7(8): e1002172.
  • Weisel, F., Appelt, U., Schneider, A., Horlitz, J., van Rooijen, N., Korner, H., Mach, M., Winkler, T.H. (2010). Unique requirements for reactivation of virus-specific memory B lymphocytes. J Immunol. 185: 4011-4021.
  • Burkhardt, C., Himmelein, S., Britt, W., Winkler, T., Mach, M. (2009). The glycoprotein N subtypes of human cytomegalovirus induce a strain-specific antibody response during natural infection. J Gen Virol. 90: 1951-1961.